Retatrutide-Associated Improvements in Cardiovascular Risk Biomarkers in Adults With Obesity With or Without Type 2 Diabetes

Formally recognizing insulin resistance as a distinct disease, rather than just a risk factor, would facilitate earlier diagnosis and standardized treatment.

A trial of 6,238 heart attack survivors in France found stopping beta blockers about as safe as staying on them: 17.2% who stopped had a problem, versus 15.9% who stayed.

In Uganda, 1,784 children under 2 got yellow fever vaccine at full, half or one fifth strength

Treatment of Kratom Withdrawal and Dependence With Buprenorphine/Naloxone: A Case Series and Systematic Literature Review

[JAMA Psychiatry] The EPIsoDE randomized clinical trial of psilocybin for treatment-resistant depression yields inconclusive primary results, finding no statistically significant difference in 6-week response rates between 25 mg psilocybin (17%) and active placebo (10.6%).

Systematic review of 155 studies finds updated COVID-19 vaccines provide meaningful protection against hospitalization and death, especially in older adults

Vaccine protects against multiple fungal infections without hurting gut: Naturally occurring fungi and bacteria in gut microbiome unharmed by new pan-fungal vaccine that achieved protective immunity in primates against life-threatening fungal infections that kill millions each year.

A Czech trial of 558 people with dangerous lung clots found feeding clot dissolving drugs straight into the lung artery cut deaths and repeat clots to under 1%…

Magnetic Mitohormesis May Represent a Non-Invasive Restorative Therapy for X-Linked Muscular Dystrophies