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A fungus resistant to all 4 types of antifungal drugs has been found in a hospital patient in Kenya, only the 2nd case ever recorded worldwide after New York in 2022

Smart glasses are about to create a major privacy crisis

Study Finds That Detecting Persistence Transitions in Nonlinear Dynamical Systems Depends on What Is Measured

Singapore physicists build the world's most accurate optical atomic clock using a single lutetium ion, measuring time precision to 19 decimal places.

One small 2006 trial of just 40 kids in Iran may have tipped the scales in favour of prescribing Prozac for childhood depression

Reactivation of the embryonic ζ-globin gene ameliorates severe forms of α-thalassemia

Materials scientists develop ductile and scalable 3 GPa (435 ksi) steel via a hierarchical microstructural architecture

Type 2 immune history trains lung macrophages for viral disease tolerance

Researchers traced decades long wobbles in day length to gravity pulling between the spinning inner core and the mantle above it, not magnetism as long assumed.

Amino acid mapping–guided scaffold selection and hit identification of histidine kinase inhibitors from a virtual library of over 12 million compounds

Tonicity drives collecting duct maturation in the mammalian kidney

A model learned from experimental data improves control of a robotic joint powered by artificial muscles

Function-preserving watermarking of AI-generated proteins

Senolytics dasatinib and quercetin in metabolic dysfunction-associated steatohepatitis: a proof-of-principle randomized, controlled trial

First for RNA therapy: man with rare motor-neuron disease improves after treatment

Climate models suggest that by 2090, particles that seed clouds could rise up to 16% in the High Arctic but fall by up to 31% in the wetter Maritime Arctic.

Intestinal infections cause antigen-specific CD4+ T cells to migrate from the gut and establish long-lived memory in the brain and meninges, a mechanism the authors link to anxiety and depression in inflammatory bowel disease

Two parallel neural ectoderm progenitors contribute to the developing brain

Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria

Defining collectivism as duties in relationships rather than generalized warmth improves predictive validity in 100 cultures

A queen odour mediates reproductive suppression in a eusocial mammal

Ca 5% of white adults in the US support white nationalism, but among young white men, it's 13.5%

Oral small-molecule GLP-1 receptor agonist safiglipron in early type 2 diabetes: a randomized, double-blind, placebo-controlled trial

Human brain cells transplanted into mice in ‘most extensive’ integration ever

Deletion of a distal IRF4 element prevents inflammation-induced reprogramming of human regulatory T cell fate

In a US trial, teclistamab wiped out cancer completely in 78% of high risk myeloma patients, against 0% on standard treatment, and cut two year progression to 8%.

Association between the triglyceride/high-density lipoprotein cholesterol ratio and isolated nocturnal hypertension | Journal of Human Hypertension

A divergent betacoronavirus with a functional furin cleavage site in South American bats

Individual locomotor bias drives counterclockwise motion in pedestrian crowds

Teenage girls show higher prevalence of internalizing problems than boys: depressive symptoms (15.9% versus 8.2%) and suicidal ideation (29.8% versus 18.1%)

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