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Microdosing Psilocybin: No Benefit in Cognitive, Affective, or Social Function in Healthy Individuals

Long-term antidepressant effects of psilocybin linked to functional brain changes - a single dose of psilocybin altered the electrical properties of brain cells in rats for months, even after physical changes to the neurons had disappeared.

Psilocybin may reduce depressive symptoms in cancer patients, with mixed effects on anxiety and time-dependent improvements in spiritual well-being and quality of life.

Psilocybin triggers activity-dependent rewiring of large-scale cortical networks

Psilocybin shown to markedly reduce chronic pain and neuroinflammation

A small early-phase human clinical study suggests that a single 10 mg dose of psilocybin transiently reduces compulsive, but not obsessive, symptoms in adults with OCD, with effects peaking at one week and no full psychedelic experience.

A new study shows psilocybin reshapes brain circuits linked to depression by weakening rigid cortico-cortical loops that trap people in negative thinking and strengthening sensory-motor pathways that help restore cognitive flexibility.

Five Years After Psilocybin Therapy, Two-Thirds Remain Free from Depression

Psilocybin therapy linked to reduced suicidal thoughts in people with psychiatric disorders

A single dose of psilocybin shown to rewire brain circuits in mice, providing up to two weeks of relief from both chronic pain and depression-like symptoms, offering a potential non-addictive alternative to opioids

Psilocybin during the postpartum period induces long-lasting adverse effects in both mouse mothers their and offspring

Psilocybin therapy linked to lasting depression remission five years later

Single dose of psilocybin linked to lasting symptom relief in treatment-resistant depression

Researchers tested 12 “magic mushroom” edible products sold in Portland, Ore., and found no trace of psilocybin, the hallucinogenic compound that gives magic mushrooms their name

A Study From Emory University Finds That Psilocybin, a Compound Found in Psychedelic Mushrooms, increases the longevity of human fibroblast cells by 57%

A meta-analysis has relativised the efficacy of psilocybin in the treatment of patients with depression

Psilocybin treatment extends cellular lifespan, improves survival of aged mice

Psilocybin treatment extends cellular lifespan, improves survival of aged mice

Psilocybin shows promise as anti-aging therapy

Military veterans who attended retreats involving psychedelic substances like psilocybin or ayahuasca experienced substantial short-term improvements in mental health…

Psilocybin decreases depression and anxiety in cancer patients (2016)

What happens when clergy take psilocybin

Single high dose of psilocybin, combined with psychological support, led to reductions in alcohol use among people with severe alcohol use disorder

Psychedelics may buffer against PTSD: Survivors of Nova music festival massacre in Israel on October 7, 2023 who consumed classic psychedelics (psilocybin, LSD, mescaline, or 2C-B) at the time reported significantly lower levels of anxiety and post-traumatic symptoms 3 weeks after the attack.

Psilocybin reduced depression symptoms as much as leading antidepressant (2021)

A single dose of psilocybin might help reduce symptoms in treatment-resistant depression

Use of psilocybin, the hallucinogenic chemical found in what is known as “magic mushrooms,” has increased significantly nationwide since 2019, according to a new study led by researchers at the University of Colorado Anschutz Medical Campus and Rocky Mountain Poison and Drug Safety.

Psilocybin’s impact on mental wellbeing varies by race, study finds

Psilocybin increases emotional empathy in depressed individuals, study finds | These improvements lasted for at least two weeks after treatment.

People who have been to an emergency department or hospitalised after using hallucinogens such as ketamine, psilocybin, LSD, and MDMA are at a 2.6-fold higher risk of dying of any cause over the next five years

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