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News coverage of psilocybin often outpaces the science, systematic review finds

A single dose of psilocybin eased depression within days, but its edge over placebo faded within a year

MDMA and Psilocybin Regulates Anxiety in a Rat Model

Magic mushroom compound psilocybin grows new brain connections within 24 hours and repairs circuits damaged by chronic stress in mice

‘Unparalleled’ study finds psilocybin protects against nerve damage from chemotherapy

Magic mushroom compound may prevent chemotherapy pain: « Research in mice finds that psilocybin protects against nerve damage and sensitivity caused by common cancer drugs

First human trial of psilocin since the 1960s reveals better tolerability than psilocybin

Psilocybin restores spatial memory but not fronto-hippocampal synchrony in a rat model of Alzheimer’s disease

[JAMA Psychiatry] The EPIsoDE randomized clinical trial of psilocybin for treatment-resistant depression yields inconclusive primary results, finding no statistically significant difference in 6-week response rates between 25 mg psilocybin (17%) and active placebo (10.6%).

Could psilocybin be the key to treating anorexia?

America's First Legal Psilocybin Program Treated 346 People

Psilocybin reverses depressive behaviors and restores brain cell growth in stressed rats

Psilocybin Might Make Your Brain Live in the Moment— Psychedelics are often associated with disconnecting from reality, but a recent neuroimaging study found psilocybin can actually make our brain activity more attuned to the world around us.

In recent years, there has been growing interest among adults with ADHD in the practice of microdosing classic psychedelics such as psilocybin and LSD

Rapid-acting antidepressants such as ketamine and psilocybin appear to reduce treatment-resistant depression by altering immune-brain signaling, with shared immune biomarkers that may help predict which patients are most likely to benefit from these treatments

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression

Psilocybin-assisted therapy shows promise for veterans with severe, treatment-resistant PTSD

Woman with Alzheimer's starts conversing again after taking psilocybin

One or two psilocybin doses still lifting depression a year on

A single dose of psilocybin, paired with psychological support, provides months of relief from chronic suicidal thoughts in new study

Improvement in advanced Alzheimer’s disease following high-dose psilocybin

Case report: transient return of speech and continence in advanced dementia patient after 5g psilocybin mushrooms

A single dose of psilocybin - the active compound in magic mushrooms - reduces nerve pain for up to a month and makes a widely used painkiller work more effectively, finds a new study in mice

Tobacco plant can produce five psychedelics, including psilocybin and DMT

Human brain changes after first psilocybin use

Repeated doses of psilocybin show promise for treating obsessive-compulsive disorder

A single dose of psilocybin can lead to lasting shifts in a person’s life values, such as an increased appreciation for life and greater self-acceptance

Thousands of Americans Treated With Psilocybin in 2025

Psilocybin might not be the most psychoactive ingredient in magic mushrooms

"A new study suggests Psilocybin may do more than just cause a temporary trip and could actually rewire the brain"

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