People who use both cannabis and tobacco show higher brain levels of FAAH — an enzyme that breaks down mood-regulating anandamide — than cannabis-only users, possibly explaining why mixing the two is tied to worse mental health and harder quitting.

Researchers identify key genes linked to cannabis use and its frequency, particularly CADM2 and GRM3, tied to brain communication and impulsivity

Cannabis use linked to short-term relief of PTSD symptoms in veterans

A study of 379,000 US adults found daily cannabis smoking linked to higher odds of asthma and COPD, even in people who never smoked tobacco.

Cannabis use linked to stronger emotional responses but also better recovery in people with anxiety

In the largest such study to date, frequent cannabis users did not display impairments in driving performance after at least 48 hours of abstinence

Comment on Bar-Sela et al. Cannabis Consumption Used by Cancer Patients During Immunotherapy Correlates with Poor Clinical Outcome

Insomnia patients using medical cannabis reported improved sleep quality and reduced anxiety, depression, and pain, according to a new study tracking 125 patients for 18 months

Cannabis use associated with quadrupled risk of developing type 2 diabetes

Cannabis compounds THC and cannabidiol (CBD) have opposing effects on brain function—and combining the two produces more muted changes than THC alone, finds new neuroimaging study in rats to compare how these cannabis-derived compounds alter patterns of communication and blood flow in the brain.