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Big Oil asks Supreme Court to kill climate lawsuits before trial

A 1970s heart treatment that squeezes your legs with inflatable cuffs improved memory and thinking in 84% of people with early Alzheimer’s in a 190-person trial

A randomized clinical trial found children whose mothers took phosphatidylcholine, a form of choline found naturally in foods, had fewer social withdrawal problems and scored higher on cognitive tests than children whose mothers received a placebo.

A clinical trial has found hydrodissection, injecting saline to separate a trapped nerve from surrounding tissue, provides carpal tunnel relief lasting up to 6 months…

Cops raid office of RFK Jr. allies planning “unethical” vaccine trial on babies

In a small randomized trial of people with acute hepatic porphyria, a rare inherited disorder, 5 of 6 who got a placebo instead of a scheduled IV hemin dose had an attack within a week…

Journal of Trial and Error

A randomized controlled trial of 227 adults aged 18–39 found a three-week online self-compassion meditation program improved body appreciation and psychological well-being while reducing body dissatisfaction and self-judgment

A 12-week clinical trial found a daily supplement combining berberine, white mulberry extract, and chromium helped adults with obesity lose 2.35 kg of body fat and improve their insulin sensitivity by 28% compared to a placebo.

In early clinical trial, people with Type 1 diabetes are able to go off insulin

Clinical trial of a prion disease drug candidate begins enrolling participants

Older vegetarians got just as much stronger as meat eaters from weight training, but meat eaters gained roughly 70% more arm and leg muscle (0.66 kg vs 0.38 kg) in a 12-week trial of 108 adults over 55

One small 2006 trial of just 40 kids in Iran may have tipped the scales in favour of prescribing Prozac for childhood depression

Landmark NEJM Trial: Restricting Fluids in Septic Shock Shows No 90-Day Benefit Over Standard Care

Uber Begins Self-Driving Robotaxi Trial In Manchester

New study: Topical Urolithin A reduces wrinkle depth vs placebo after 8 weeks in a randomized clinical trial, among other findings

Changes in ectopic lipids, insulin sensitivity, and beta cell function after a low-fat vegan diet in adults with type 2 diabetes: a 16-week single-arm clinical trial

A randomised trial (405 UK families) showed giving 2-year-olds the live attenuated nasal flu vaccine doubled the odds of pneumococcal acquisition among household contacts at 14 days, linked pneumococcal carriage density; effects were no longer significant by day 28.

PVX-001: open-source Covid-19 vaccine starts Phase 1 trial

A natural protein that's up to 2,000 times sweeter than sugar from a West African fruit cut blood sugar spikes from ice cream by about half in a trial of 101 adults with fatty liver disease, with even bigger drops in people with type 2 diabetes and no serious side effects were reported in the study.

A 1,000-patient JAMA trial shows cold-stored platelets (up to 21 days) are noninferior to standard room-temp platelets for active bleeding, potentially slashing waste and expanding availability.

Senolytics dasatinib and quercetin in metabolic dysfunction-associated steatohepatitis: a proof-of-principle randomized, controlled trial

In a 104 week trial of 493 adults with overweight or obesity, diet soft drinks were equivalent to water for long-term weight management, with no evidence they disrupted appetite regulation or caused long term metabolic harm

Tesla faces major trial for alleged bias against Black workers, after years of lawsuits

Alzheimer's trial to test drug on people without symptoms to test prevention

A pill nearly halved deaths from head injury In a Swedish led trial in a low income hospital, 20% given the drug Salovum died within 30 days, against 39% on standard care

Oral small-molecule GLP-1 receptor agonist safiglipron in early type 2 diabetes: a randomized, double-blind, placebo-controlled trial

First human trial of psilocin since the 1960s reveals better tolerability than psilocybin

Clinical trial published in JAMA Network Open shows soft lumbar belts reduce daily limitations and pain during movement for nonspecific lower back pain

In a US trial, teclistamab wiped out cancer completely in 78% of high risk myeloma patients, against 0% on standard treatment, and cut two year progression to 8%.

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