Structural insights into lipid membrane binding by human ferlins | The EMBO Journal

New research reveals S-acylation of ROT4 peptide crucial for plant immunity, enhancing pathogen resistance by modulating signaling pathways

Immunotherapy targeting isoDGR-protein damage extends lifespan in a mouse model of protein deamidation

Trained immunity induced by high-salt diet impedes stroke recovery (Nov 2023)

Potential rabies treatment discovered with a monoclonal antibody, F11. Rabies virus is fatal once it reaches the central nervous system

Automated assembly – molecular mechanisms from text mining and curated databases

A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability

Researchers from The University of Queensland have determined how Botox – a drug made from a deadly biological substance – enters brain cells.

Low temperature and mTOR inhibition favor stem cell maintenance in human keratinocyte cultures (May 2023)

Nerve regeneration by interferon intervention in aging brain

Antitumor T-cell function requires CPEB4-mediated adaptation to chronic endoplasmic reticulum stress

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10 (Feb 2023)

A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs (Nov 2022)

Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids

Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia (Feb 2022)

Ketone body oxidation increases cardiac endothelial cell proliferation (Feb 2022)

A microRNA signature that correlates with cognition and is a target against cognitive decline

Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming

Vegan diet in young children remodels metabolism and challenges the statuses of essential nutrients

Chronic cold exposure enhances glucose oxidation in brown adipose tissue

Scientists discover new breakthrough in treatment for cancer hair loss

Removing senescent cardiac muscle cells from the hearts of aged mice, both genetically and using drugs, restores cardiac health.

Scientists have turned ordinary mice into super-smellers by boosting the number of a certain type of cell in the animals’ brains.

Scientists at the University of Birmingham have discovered a protein that could hold the key to novel gene therapies for skin problems including psoriasis—a common, chronic skin disease that affects over 100 million people worldwide.

Periodic fasting starves cisplatin‐resistant cancers to death

Single-injection FGF21 gene therapy treatment for obesity and insulin resistance succeeds in two different mouse models of obesity, induced either by diet or by genetic mutation, counteracting obesity and insulin resistance for 12+ months.

Are scientists a workforce? – Or, how Dr. Frankenstein made biomedical research sick