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American Medical Association Backs Classification of Nearsightedness as Disease

First for RNA therapy: man with rare motor-neuron disease improves after treatment

Blacklegged ticks in Western North Carolina now match Northeast Lyme disease infection rates (~40%), confirming the southern Appalachia expansion of northern vector lineages

A unified evolutionary explanation of Parkinson's disease

Blood-Brain Barrier Successfully Repaired in Alzheimer's Models: in Alzheimer's disease, this protective border can begin to leak

Meat intake is associated with increased fatty liver disease risk, particularly in genetically susceptible individuals

New research found greater amounts of REM and deep sleep were associated with lower risks of dozens of diseases, while less than 5 hours of total sleep was linked to high risks of disease

Cerebral Palsy Might Not Actually Be a Disease, Scientists Say

The reduced risk of heart disease seen in people who are overweight or have obesity taking the weight loss drug semaglutide may not be due to a drop in weight alone

Global disease outbreak maps track healthcare access far more than actual ecology

Intestinal infections cause antigen-specific CD4+ T cells to migrate from the gut and establish long-lived memory in the brain and meninges, a mechanism the authors link to anxiety and depression in inflammatory bowel disease

Large Study of 318,000 People Links Subclinical Liver Disease to 2.5× Higher Cardiovascular Risk

A new study shows that even a small reduction in systolic blood pressure can help slow down the progression of cerebral small vessel disease, reducing the risk of cognitive decline and dementia.

U of A Researchers Led by Dr. Satyabrata Kar Uncover Breakthrough Approach to Treating Alzheimer's Disease

A large study says a higher amount of midlife visceral fat is strongly linked to increased brain inflammation and early biological signs of Alzheimer's disease up to 20 years before memory symptoms appear.

Psilocybin restores spatial memory but not fronto-hippocampal synchrony in a rat model of Alzheimer’s disease

Hot weather kills off 9.7% of disease carrying mosquitoes, but speeds up the virus in survivors and shifts human behaviour, driving a projected 76% rise in chikungunya cases.

In a prospective study of 104,806 adults followed for a median 8.1 years, greater differences in meal timing between weekdays and weekends were associated with higher cardiovascular disease risk in men

Preclinical study identifies TAB2 as a key regulator of microglial neuroinflammation in Parkinson's disease models

A new study reveals that radiation exposure can trigger brain inflammation via the eCIRP protein, which subsequently drives the accumulation of tau proteins that form the signature tangles of Alzheimer's disease.

Formally recognizing insulin resistance as a distinct disease, rather than just a risk factor, would facilitate earlier diagnosis and standardized treatment.

Make infectious disease data boring again

An unhealthy Western-style diet was associated with a faster cognitive decline in people with a genetic risk of Alzheimer's disease, according to a study on 185 older adults followed for more than 7 years

The diabetes and weight-loss drug semaglutide was found to calm brain inflammation and accelerate cellular recovery in mice, suggesting it could potentially protect against cognitive decline and neurodegenerative conditions like Alzheimer's disease

A mysterious kidney disease has arrived in Texas

In mice, researchers found evidence that Alzheimer’s disease may originate outside the brain, with signals from other organs helping drive the neurodegenerative changes linked to memory loss and cognitive decline.

A new genomic language AI model, GPN-Star, outperforms existing models in identifying genetic variants associated with inherited traits, including variants linked to disease.

A new study reveals that Australia's pre-colonization Indigenous population was approximately 2.22 million people, up to 7 times larger than previously estimated, exposing a devastating demographic catastrophe caused by subsequent disease and colonial violence.

Atlas of the brain’s striatum could guide researchers to new drug treatments: « A new study reveals insights into populations of neurons affected by Huntington’s disease, schizophrenia…

Common genetic marker associated with faster Parkinson’s disease progression: People who carried the Melanocortin 1 receptor (MC1R) loss-of-function variants experienced 30% to 50% faster motor decline than non-carriers across two independent cohorts

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