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A trial of 6,238 heart attack survivors in France found stopping beta blockers about as safe as staying on them: 17.2% who stopped had a problem, versus 15.9% who stayed.

In a 70 person US safety trial, Kylo 11 lowered lipoprotein(a), a heart risk marker diet can't touch, by up to 97% over 48 weeks

In a trial of 393 patients in the United States, the highest dose cut eczema skin symptoms by 61%, against 31% on a placebo, after 16 weeks.

Study of over 75,000 women with HER2-negative breast cancer found those with low-to-moderate estrogen receptor levels had poorer survival than those with high levels, suggesting breast cancer may be better classified along a spectrum of estrogen receptor expression.

Dopaminergic vulnerability in long COVID: striatal PET imaging at the brain-body interface

Plant-Based Diets, Ultra-Processed Foods, and Risks of Mortality and Major Chronic Diseases

New research shows how generative AI may intensify suicide risk among children and adolescents through thwarted belongingness, perceived burdensomeness, and capability for lethal self-injury

Elecoglipron, an oral GLP-1 drug taken daily, demonstrated clinically meaningful weight reductions in adults with obesity or overweight, in a new randomised, placebo-controlled clinical trial.

Podcast with some of the authors from The Lancet Special issue in Neurology: advances and challenges in the field

Photobiomodulation for cognitive dysfunction (Brain Fog) in post-COVID-19 condition: a randomized double-blind sham-controlled pilot trial

New Imaging Technique Reveals Alzheimer’s Tau Sooner Than Current Standard

Lancet Digital Health Viewpoint proposes a four-part functional typology of "AI psychosis": large language models can act as catalyst (precipitating new symptoms), amplifier (worsening existing symptoms), co-author (developing harmful narratives), or object (becoming the focus of delusional belief).

Virtual reality-based cognitive remediation versus virtual reality control in people with mood or psychosis spectrum disorders in Denmark: a single-centre, double-blind, randomised controlled trial

Impact of two decades of humanitarian and development assistance and the projected mortality consequences of current defunding to 2030: retrospective evaluation and forecasting analysis

Global, regional, and national burden of meningitis, its risk factors, and aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Climate change could drive millions into physical inactivity by 2050 as rising heat makes outdoor exercise unsafe

Study suggests anxiety, insomnia and ADHD may share the same underlying brain state

Phase 3 Randomized Controlled Trial (TORPEdO) finds no significant difference in 1-year quality of life or swallowing outcomes between expensive Proton Beam Therapy and modern Intensity-Modulated Radiotherapy (IMRT) for throat cancer.

New analysis in The Lancet finds the 2025-2030 US Dietary Guidelines contain a profound internal incoherence, promoting animal proteins and full-fat dairy while claiming to limit saturated fats a paradox researchers say prioritizes industry profits over public health.

In a Phase 3 trial, the daily pill orforglipron outperformed oral semaglutide for weight loss (15-20 lbs) and cardiovascular markers

Asbestos, talc, and The Lancet's 1977 publication

Artificial intelligence-associated delusions and large language models

Robert F Kennedy Jr: 1 year of failure

A massive 30-year study reveals that climate-friendly diets provide unexpectedly strong nutritional outcomes and better energy for the body without meat-related deficiencies

World-first stem-cell therapy shows promise for treating spina bifida in the womb

The Lancet Series on Ultra-processed Foods and Human Health

Meta-analysis finds that exercise interventions significantly improved the quality of life of women with breast cancer undergoing chemotherapy

The Lancet: Robert F Kennedy Jr: 1 year of failure

Impact of the "when the fun stops, stop" gambling message on online gambling

A new study using satellites to monitor 1,700 California ZIP codes shows that every 200 new EVs led to a 1.1% drop in nitrogen dioxide between 2019 and 2023, proving that even small upticks in adoption measurably improve air quality and reduce risks to heart and lung health.

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