Study of 376,511 people followed for up to 14 years found participation in colorectal cancer screening was associated with a 43% lower risk of dying from the disease, while being invited to screening was associated with a 26% lower risk.

Nobel Disease

GLP-1 drugs like Ozempic may help clear Alzheimer’s disease plaques, new systematic review suggests

Deep sleep brain waves during NREM offer protection against Alzheimer’s disease, suggesting that sleep quality may help counteract the cognitive risks associated with elevated levels of the neurotransmitter orexin

Among 28,720 People With Type 2 Diabetes, Women Were More Likely to Develop Mental Health Conditions, While Men More Often Developed Cardiovascular and Kidney Disease

Conceptual shift in TBI classification from the Glasgow Coma Scale to a new framework that integrates clinical and imaging features, biomarkers, and modifiers to improve disease characterization and describe disease trajectories

GLP-1 weight loss drugs such as Ozempic are linked with a lower risk of age‐related macular degeneration (AMD), a common eye disease that is the leading cause of irreversible vision loss in older adults.

The mRNA-LNP vaccine encoding viral VP2 confers effective protection against novel variant infectious bursal disease virus (nVarIBDV)

Show HN: 35k+ paper psychedelic library that knows LSD from Lumpy Skin Disease

Depression is linked to a smaller volume in a memory-related hippocampal region, according to brain scans of 2,009 cognitively healthy adults aged 50–90, independent of body mass index, physical activity, and several major biological indicators of Alzheimer's disease risk.

Researchers found a "genetic switch" that triggers neurodegeneration in both a rare childhood dementia and Alzheimer's disease due to waste build-up in microglia

Unexpected structure detected in the brains of humans and mice with Alzheimer’s disease - scientists pinpointed an entirely new pathological basis for the disease: an accumulation of mitochondrial plaques, due to the brain's inability to recycle its failing mitochondria.

A 38 year study of ~1 million adults (30 to 95 y) found lower red and processed meat intake was associated with a 1–5% lower risk of death from all causes, heart disease and cancer, while eating only white meat was linked to a 5–7% lower risk of all-cause mortality

Putting money where their mouth is: Anthropic’s Claude autonomously designs disease-targeting proteins with real wet-lab proof, hitting a 35% success rate vs 10–15% human average

Newborns immunized against RSV also had a 36% lower risk of invasive pneumococcal disease.

Risk of Parkinson’s disease may increase with prolonged exposure to road traffic noise

Bryan Johnson, the millionaire biohacker who wants to live forever, diagnosed with incurable autoimmune disease

Colossus 2 data center installed 59 natural gas turbines without permission, report claims thousands of tons of pollutants reportedly impact Black communities in Mississippi already suffering from elevated lung disease rates

Genetic base editing treats Huntington’s disease in mice - A gene editing tool designed to precisely rewrite the gene that causes Huntington’s disease reduced toxic protein fragments and symptoms associated with the disease.

A 10-year study of 179,000 adults reveals that diets rich in vitamin K1, found in leafy greens like spinach and kale, are linked to stronger lung function and a 16% lower risk of developing chronic obstructive pulmonary disease (COPD)…

ADHD and autism showed no signs of accelerated brain aging. Alzheimer’s disease ranks first

Scientists link oral bacteria to heart disease and cognitive decline

Caffeine and Cardiovascular Disease: AHA Scientific Statement

A healthy plant-based diet was linked to a 40% lower risk of getting a first cardiometabolic disease (especially diabetes), and 21% lower risk of multiple cardiometabolic diseases…

Biohacker seeking immortality afflicted with incurable 'stomach eating' disease

Study Finds NFL Players Four Times More Likely to Die Due to Neurodegenerative Disease

Ex-smokers remain at higher risk of lung disease because some lung cells recover after quitting while others retain lasting changes to tissue structure, immune function and blood vessel health, according to an analysis of more than 100,000 lung cells across 40+ cell types from 21 people

Study finds that the adult thymus may still matter for longevity: in over 27,000 people, an imaging-based thymic-health score was associated with 12-year mortality from cancer, heart disease…

No statistical link between use of semaglutide and other GLP-1 drugs and risk of degenerative eye disease in adults with type 2 diabetes

Study Finds 1 in 3 Americans Without Heart Disease Miss New Cholesterol Goals—and 3 in 4 Go Untreated

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