Estrogen loss impairs NRF2-mediated antioxidant defenses, increasing susceptibility to infertility and cardiovascular disease in women

Circadian dysfunction correlates with disease severity in neurodegeneration, highlighting the molecular clock as a key biomarker and therapeutic target

Soluble N-terminal region of prion protein causes rapid neurodegeneration in prion disease - Science Advances

Greater adherence to a healthful plant-based diet is associated with significantly lower all-cause and cardiovascular disease mortality in adults with cardiovascular-kidney-metabolic (CKM) syndrome, an association partially mediated by leukocyte telomere length…

Stress-Related Brain Signals Drive Risk of Cardiovascular Disease in People with Depression and Anxiety

UQ’s Queensland Brain Institute researchers showed scanning ultrasound is safe and well-tolerated in a first-in-human pilot study—an important step toward Alzheimer’s disease treatments.

Continuous cough monitoring accurately quantifies disease burden and day-to-day variability, enabling earlier detection of patient deterioration, more sensitive clinical trial endpoints…

CU Anschutz scientists have discovered that while brain neuron changes, including cell loss, may begin in early life, a drug long-approved for other conditions might be repurposed to slow this damage, offering new hope for those with Alzheimer’s disease and other cognition issues.

The Lancet Series on Alzheimer's Disease-composed of 3 papers highlighting latest advances in diagnosis, treatment and controversies in the field

Prime editing-installed suppressor tRNAs for disease-agnostic genome editing

Alternative sweetener sorbitol, commonly found in zero-calorie candies and in some fruits and vegetables, linked to liver disease

A common type of inflammatory bowel disease has been linked to toxic bacteria

Gum disease and tooth decay hit men harder – and now we know why

One in two people in the U.S just over half of the population, is affected by a neurological disease or disorder

Natural molecule (NAD⁺) reverses memory loss seen in Alzheimer's disease in animal models

Manganese is Lyme disease's double-edge sword

One in two people in the US is affected by a neurological disease or disorder

Scientists have uncovered a surprising connection between sugar metabolism and alcohol addiction, identifying a potential new therapeutic target for treating alcohol-associated liver disease (ALD) and alcohol use disorder (AUD).

Epstein-Barr virus appears to be trigger of lupus disease, say scientists

Scientists at Duke University discover a Muscovy duck virus that evades human immune detection and engineer it to create an immune-evasive gene therapy vector for Pompe disease in a mouse model

A study shows that Other Specified Feeding or Eating Disorder (OSFED) is as harmful as anorexia and bulimia, often presenting with more severe symptoms, despite often being viewed as a less serious disease

CDC to end all monkey research; will phase out HIV, infectious disease studies

Phase I/II trial of AMT-130 gene therapy for Huntington’s disease reports slowed disease progression versus natural history cohort

Ticker: Don't die of heart disease

Waist-to-height ratio outperforms BMI in predicting heart disease risk

Hypertension affects the brain much earlier than expected: « The changes help explain why hypertension is a major risk factor for developing cognitive disorders, such as vascular cognitive impairment and Alzheimer’s disease

Chronic stress upregulates cortisol and generates ROS, driving kidney disease progression

According to early-stage scientific findings, shifting toward a plant-based diet abundant in fruits, vegetables, nuts and legumes may help protect against heart disease linked to hypertension and may even help reverse certain aspects of it…

Chronic Kidney Disease now affects more than 780 million people worldwide

A fungal infection solution could help eliminate up to 86% of malaria-carrying mosquitoes, offering a powerful new tool in the global fight against the disease, according to new research.

More →