Scientists have recently discovered that psilocybin, the active ingredient in “magic mushrooms,” can significantly reduce chronic pain in rats

A study examining outcomes of a 2021 clinical trial that found psilocybin effectively treated major depressive disorder linked a stronger relationship between study participants & clinicians to lower depression scores 1 year later-pointing to the importance of the therapeutic alliance.

Scientists investigate whether a compound found in magic mushrooms, psilocybin, could play a role in combating the effects of diabetes

Therapists report significant psychological risks in psilocybin-assisted treatments

A new study did not find a significant link between patients’ expectations and their actual responses to psilocybin therapy in the treatment of depression

Psychological experiences underlie psilocybin therapy's success: Mystical experiences and ego dissolution identified as key mediators

A recent study reveals new insights into how psilocybin-assisted therapy modifies brain function in people with alcohol use disorder

A new study suggests possible benefits of using psilocybin-containing mushroom extract over its chemically synthesized counterpart

Individuals who use psychedelic substances like LSD and psilocybin may experience a significant increase in unusual visual phenomena, such as seeing patterns or intense colors that are not there

By observing the effects of psilocybin, a compound found in psychedelic “magic” mushrooms, on larval zebrafish, scientists uncovered that it not only stimulates exploratory behavior but also buffers against stress-induced changes in activity patterns.

Low doses of MDMA, commonly known as ecstasy, can help to reduce the challenging effects and enhance the positive experiences associated with psychedelic drugs like LSD (lysergic acid diethylamide) and psilocybin…

A recent study found a considerable diversity of experiences by gazing into the mirror while under the influence of psilocybin

Phylogenomics of the psychoactive mushroom genus Psilocybe and evolution of the psilocybin biosynthetic gene cluster

Nearly 4 out of 5 Canadians believe that the use of psilocybin, the active ingredient in hallucinogenic mushrooms, is an acceptable medical approach to treat existential distress in patients suffering from a serious and incurable disease

Psilocybin, a compound found in psychedelic “magic mushrooms,” significantly alters brain connectivity in rats

New study reveals promising effects of psilocybin in treating severe depression in bipolar II disorder patients

Oregon launches legal psilocybin access to the public

Scientists developed new compounds derived from psilocybin, the active ingredient in “magic mushrooms”, that are designed to reduce the psychedelic effects associated with psilocybin while maintaining its therapeutic benefits.

Amanita Muscaria vs. Psychedelic Mushrooms (Psilocybin): What's the Difference?

Single-Dose Psilocybin for Major Depressive Disorder: Randomized Clinical Trial

Psychedelic psilocybin-assisted therapy reduces depressive symptoms in adults with cancer and depression

Psilocybin-assisted group therapy in patients with cancer diagnosed with a major depressive disorder was safe and feasible

Psilocybin analog leads to 79% of remission in mid-stage depression trial

Exploring the Impact of Psilocybin on the Immune System: Insights from a Controlled Study on Healthy Participants

Psilocybin-Assisted Therapy for Depression: A review and meta-Analysis finds psilocybin to have a significantly greater antidepressant effect compared to the placebo drug used

Psilocybin might be effective for treatment-resistant depression even with ongoing SSRI use, study suggests

Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats

Benefits of psychedelics in obsessive-compulsive disorder: LSD and psilocybin have strong potential for providing long-lasting relief of patients’ symptoms

Psychedelic mushrooms and quiet quitting: Psilocybin use tied to working fewer overtime hours

Naturalistic psilocybin use associated with persisting improvement in wellbeing

More →